Run tAge pipeline separately per group factor (e.g., "tissue")
Usage
tAge_by_group(
eset,
split_by,
model_paths,
species = "mouse",
mode = "EN",
control_group_column = NULL,
control_group_label = NULL,
count_threshold = 10,
percent_threshold = 20,
min_samples = 5,
verbose = TRUE
)Arguments
- eset
An ExpressionSet from pseudobulk aggregation.
- split_by
Character. Column in pData to split by (e.g., "tissue").
- model_paths
Named list of model paths.
- species
Character. Species name.
- mode
Character. "EN" or "BR".
- control_group_column
Character or NULL. Column for control subtraction.
- control_group_label
Character or NULL. Label for control group.
- count_threshold
Integer. Gene filtering threshold.
- percent_threshold
Numeric. Gene filtering percent.
- min_samples
Integer. Minimum samples per group to run tAge. Default 5.
- verbose
Logical.